Asís Palazón

Ikerbasque Research Professor, CIC bioGUNE

Ikerbasque Research Professor and Principal Investigator of the Immuno-Oncology lab at CIC biogune, Bilbao.

Research line:

Cancer Immunology and Immunotherapy.

ERC Starting grant (2018), Marie Curie post-doctoral fellow (2012).

Previous research experience at University of Cambridge and MedImmune, Cambridge, UK.

Doctor in Pharmacy (2012) from CIMA-Universidad de Navarra, Pamplona.

Argitalpenak
Kongresuak eta Proceedings

2024

Article / Structural insights into Siglec-15 reveal glycosylation dependency for its interaction with T cells through integrin CD11b

Nature Communications

Maria Pia Lenza, Leire Egia-Mendikute, Asier Antoñana-Vildosola, Cátia O. Soares, Helena Coelho, Francisco Corzana, Alexandre Bosch, Prodhi Manisha, Jon Imanol Quintana, Iker Oyenarte, Luca Unione, María Jesús Moure, Mikel Azkargorta, Unai Atxabal, Klaudia Sobczak, Felix Elortza, James D. Sutherland, Rosa Barrio, Filipa Marcelo, Jesús Jiménez-Barbero, Asis Palazon & June Ereño-Orbea

2023

Article / The outcome of boosting mitochondrial activity in alcohol-associated liver disease is organ-dependent

Hepatology

Goikoetxea-Usandizaga, N.; Bravo, M.; Egia-Mendikute, L.; Abecia, L.; Serrano-Maciá, M.; Urdinguio, R.G.; Clos-García, M.; Rodríguez-Agudo, R.; Araujo-Legido, R.; López-Bermudo, L.; Delgado, T.C.; Lachiondo-Ortega, S.; González-Recio, I.; Gil-Pitarch, C.; Peña-Cearra, A.; Simón, J.; Benedé-Ubieto, R.; Ariño, S.; Herranz, J.M.; Azkargorta, M.; Salazar-Bermeo, J.; Martí, N.; Varela-Rey, M.; Falcón-Pérez, J.M.; Lorenzo, Ó.; Nogueiras, R.; Elortza, F.; Nevzorova, Y.A.; Cubero, F.J.; Saura, D.; Martínez-Cruz, L.A.; Sabio, G.; Palazón, A.; Sancho-Bru, P.; Elguezabal, N.; Fraga, M.F.; Ávila, M.A.; Bataller, R.; Marín, J.J.G.; Martín, F.; Martínez-Chantar, M.L.

Article / Structural insights into Siglec-15 reveal glycosylation dependency for its interaction with T cells through integrin CD11b

Nature Communications

Lenza, M.P.; Egia-Mendikute, L.; Antoñana-Vildosola, A.; Soares, C.O.; Coelho, H.; Corzana, F.; Bosch, A.; Manisha, P.; Quintana, J.I.; Oyenarte, I.; Unione, L.; Moure, M.J.; Azkargorta, M.; Atxabal, U.; Sobczak, K.; Elortza, F.; Sutherland, J.D.; Barrio, R.; Marcelo, F.; Jiménez-Barbero, J.; Palazon, A.; Ereño-Orbea, J.

Article / Factor-inhibiting HIF (FIH) promotes lung cancer progression

JCI Insight

Río, A.G.D.; Prieto-Fernández, E.; Egia-Mendikute, L.; Antoñana-Vildosola, A.; Jimenez-Lasheras, B.; Lee, S.Y.; Barreira-Manrique, A.; Zanetti, S.R.; Blas, A.d.; Velasco-Beltrán, P.; Bosch, A.; Aransay, A.M.; Palazon, A.

2022

Article / Assessing the Mobility of Severe Acute Respiratory Syndrome Coronavirus-2 Spike Protein Glycans by Structural and Computational Methods

Frontiers in Microbiology

Stagnoli, S.; Peccati, F.; Connell, S.R.; Martinez-Castillo, A.; Charro, D.; Millet, O.; Bruzzone, C.; Palazon, A.; Ardá, A.; Jiménez-Barbero, J.; Ereño-Orbea, J.; Abrescia, N.G.A.; Jiménez-Osés, G.

Article / Stromal oncostatin M cytokine promotes breast cancer progression by reprogramming the tumor microenvironment

Journal of Clinical Investigation

Araujo, A.M.; Abaurrea, A.; Azcoaga, P.; López-Velazco, J.I.; Manzano, S.; Rodriguez, J.; Rezola, R.; Egia-Mendikute, L.; Valdés-Mora, F.; Flores, J.M.; Jenkins, L.; Pulido, L.; Osorio-Querejeta, I.; Fernández-Nogueira, P.; Ferrari, N.; Viera, C.; Martín-Martín, N.; Tzankov, A.; Eppenberger-Castori, S.; Alvarez-Lopez, I.; Urruticoechea, A.; Bragado, P.; Coleman, N.; Palazón, A.; Carracedo, A.; Gallego-Ortega, D.; Calvo, F.; Isacke, C.M.; Caffarel, M.M.; Lawrie, C.H.

Article / The spike of SARS-CoV-2 promotes metabolic rewiring in hepatocytes

Communications Biology

Mercado-Gómez, M.; Prieto-Fernández, E.; Goikoetxea-Usandizaga, N.; Vila-Vecilla, L.; Azkargorta, M.; Bravo, M.; Serrano-Maciá, M.; Egia-Mendikute, L.; Rodríguez-Agudo, R.; Lachiondo-Ortega, S.; Lee, S.Y.; Eguileor Giné, A.; Gil-Pitarch, C.; González-Recio, I.; Simón, J.; Petrov, P.; Jover, R.; Martínez-Cruz, L.A.; Ereño-Orbea, J.; Delgado, T.C.; Elortza, F.; Jiménez-Barbero, J.; Nogueiras, R.; Prevot, V.; Palazon, A.; Martínez-Chantar, M.L.

Article / An NMR-Based Model to Investigate the Metabolic Phenoreversion of COVID-19 Patients throughout a Longitudinal Study

Metabolites

Gil-Redondo, R.; Conde, R.; Bizkarguenaga, M.; Bruzzone, C.; Laín, A.; González-Valle, B.; Iriberri, M.; Ramos-Acosta, C.; Anguita, E.; Arriaga Lariz, J.I.; España Yandiola, P.P.; Moran, M.Á.; Jiménez-Mercado, M.E.; Egia-Mendikute, L.; Seco, M.L.; Schäfer, H.; Cannet, C.; Spraul, M.; Palazón, A.; Embade, N.; Lu, S.C.; Wist, J.; Nicholson, J.K.; Mato, J.M.; Millet, O.

Article / Neddylation tunes peripheral blood mononuclear cells immune response in COVID-19 patients

Cell Death Discovery

Serrano-Maciá, M.; Lachiondo-Ortega, S.; Iruzubieta, P.; Goikoetxea-Usandizaga, N.; Bosch, A.; Egia-Mendikute, L.; Jiménez-Lasheras, B.; Azkargorta, M.; Elortza, F.; Martinez-Redondo, D.; Castro, B.; Lozano, J.J.; Nogueiras, R.; Irure-Ventura, J.; Crespo, J.; Palazón, A.; Fariñas, M.C.; Delgado, T.C.; López-Hoyos, M.; Martínez-Chantar, M.L.

Article / A flow cytometry-based neutralization assay for simultaneous evaluation of blocking antibodies against SARS-CoV-2 variants

Frontiers in Immunology

Egia-Mendikute, L.; Bosch, A.; Prieto-Fernández, E.; Vila-Vecilla, L.; Zanetti, S.R.; Lee, S.Y.; Jiménez-Lasheras, B.; García del Río, A.; Antoñana-Vildosola, A.; de Blas, A.; Velasco-Beltrán, P.; Serrano-Maciá, M.; Iruzubieta, P.; Mehrpouyan, M.; Goldberg, E.M.; Bornheimer, S.J.; Embade, N.; Martínez-Chantar, M.L.; López-Hoyos, M.; Mato, J.M.; Millet, Ó.; Palazón, A.

2021

Article / Sensitive detection of SARS-CoV-2 seroconversion by flow cytometry reveals the presence of nucleoprotein-reactive antibodies in unexposed individuals

Communications Biology

Egia-Mendikute, L.; Bosch, A.; Prieto-Fernández, E.; Lee, S.Y.; Jiménez-Lasheras, B.; García del Río, A.; Antoñana-Vildosola, A.; Bruzzone, C.; Bizkarguenaga, M.; Embade, N.; Gil-Redondo, R.; Martínez-Chantar, M.L.; López-Hoyos, M.; Abrescia, N.G.A.; Mato, J.M.; Millet, Ó.; Palazón, A.

Article / Hypoxia reduces cell attachment of SARS-CoV-2 spike protein by modulating the expression of ACE2, neuropilin-1, syndecan-1 and cellular heparan sulfate

Emerging Microbes and Infections

Prieto-Fernández, E.; Egia-Mendikute, L.; Vila-Vecilla, L.; Bosch, A.; Barreira-Manrique, A.; Lee, S.Y.; García-del Río, A.; Antoñana-Vildosola, A.; Jiménez-Lasheras, B.; Moreno-Cugnon, L.; Jiménez-Barbero, J.; Berra, E.; Ereño-Orbea, J.; Palazon, A.

2020

Article / Structural Characterization of N-Linked Glycans in the Receptor Binding Domain of the SARS-CoV-2 Spike Protein and their Interactions with Human Lectins

Angewandte Chemie - International Edition

Lenza, M.P.; Oyenarte, I.; Diercks, T.; Quintana, J.I.; Gimeno, A.; Coelho, H.; Diniz, A.; Peccati, F.; Delgado, S.; Bosch, A.; Valle, M.; Millet, O.; Abrescia, N.G.A.; Palazón, A.; Marcelo, F.; Jiménez-Osés, G.; Jiménez-Barbero, J.; Ardá, A.; Ereño-Orbea, J.

Article / Hypoxia Promotes Syndecan-3 Expression in the Tumor Microenvironment

Frontiers in Immunology

Prieto-Fernández, E.; Egia-Mendikute, L.; Bosch, A.; García del Río, A.; Jimenez-Lasheras, B.; Antoñana-Vildosola, A.; Lee, S.Y.; Palazon, A.

Review / CAR-T Cells Hit the Tumor Microenvironment: Strategies to Overcome Tumor Escape

Frontiers in Immunology

Rodriguez-Garcia, A.; Palazon, A.; Noguera-Ortega, E.; Powell, D.J.; Guedan, S.

2021

Poster presentation | Targeting SARS-CoV-2 spike protein glycans by structural and computational methods

Congress Microscopy at the Frontiers of Science - Poster presentation

Soledad Stagnoli*, Francesca Peccati, Sean R Connell, Ane Martinez-Castillo, Diego Charro, Oscar Millet, Chiara Bruzzone, Asis Palazon, Ana Ardá, Jesús Jiménez-Barbero, June Ereño-Orbea, Nicola GA Abrescia, Gonzalo Jiménez-Osés