Ikerbasque. Basque Foundation for Science

You are:
  1. Home
  2. Researcher Profiles

m_researching
Calls
logogv
Seventh Framework Programme
2012 calls are opened
annual_report11
ikerbasquenews
Zientzia Foroa
ikerboost
sciencecareers_eu

José Julio Rodríguez Arellano

José Julio Rodríguez Arellano

Ikerbasque Research Professor
(Spanish)

  • Ph.D. in Biological Sciences -Neurobiology- “Cum Laude”. From the Complutense's University of Madrid in June 1995. “Evolution of the basalocortical neuronal alterations in experimental models of Alzheimer´s disease”.
  • Over 14 years of research experience in centers in Switzerland (Novartis Pharma), France (INSERM), USA (Cornell Medical College & Florida Atlantic University) and United Kingdom (The open University & The University of Manchester).
  • Research line: My research interests are centered on the neuroanatomy and functional connectivity of neural circuits in the context of memory-related plasticity under normal and pathological conditions, investigated by in vivo and in vitro approaches.
  • Creates the new Functional Neuroanatomy Laboratory (January 2010) joining the Department of Neuroscience, Faculty of Medicine, at the University of the Basque Country, Leioa, Bilbao. From July 2011 he is also associated with the Institute BioDonostia.
  • Ikerbasque Professor

view curriculum
 download (959 KB.)

Publications

2011

J.J. Rodríguez, A. Verkhratsky (2011)
Neurogenesis in Alzheimer’s disease
Journal of Anatomy

J.J. Rodríguez, Noristani H.N., Hoover W.B., Linley S.B., Vertes R.P. (2011)
Serotonergic projections and serotonin receptor expression in the reticular nucleus of the thalamus in the rat.
Synapse

J.J. Rodríguez, H.N. Noristani, M. Olabarria, J. Fletcher, T. Summerville, C.Y. Yeh, A. Verkhratsky (2011)
Voluntary running and environmental enrichment restores impaired hippocampal neurogenesis in a triple transgenic mouse model of Alzheimer’s disease.
Curr Alzheimer’s Res.

H.N. Noristani, M. Olabarria, A. Verkhratsky, J.J. Rodríguez. (2011)
Increased hippocampal CA1 density of serotonergic terminals in a triple transgenic mouse model of Alzheimer’s disease: an ultrastructural study
Cell Death Dis.

M. Olabarria, H.N. Noristani, A. Verkhratsky., J.J. Rodríguez. (2011)
Age-dependent decrease in glutamine synthetase expression in the hippocampal astroglia of the triple transgenic Alzheimer's disease mouse model: Mechanism for deficient glutamatergic transmission?
Mol Neurodegeneration

V. Parpura, J.J. Rodríguez, A. Verkhratsky. (2011)
Calcium signalling in astroglia
Mol Cell Endocrinol.

F.E. Perrin, Y.N. Gerber, M. Teigell, N. Lonjon, G. Boniface, L. Bauchet, J.J. Rodríguez, J.P. Hugnot, A.M. Privat. (2011)
Anatomical study of serotonergic innervation and 5-HT(1A) receptor in the human spinal cord
Cell Death Dis.

2010

N.I. Medvedev, V.I. Popov, J.J. Rodríguez Arellano, G. Dallérac, H.A. Davies, P.L. Gabbott, S. Laroche, I.V. Kraev, V. Doyère and M.G. Stewart (2010)
The NMDA receptor antagonist CPP alters synapse and spine structure and impairs LTP and LTD induced morphological plasticity in the dentate gyrus of awake rats
Neuroscience

J.J. Rodríguez, J. Witton, M. Olabarria, H.N. Noristani and A. Verkhratsky (2010)
Increase in the density of resting microglia precedes neuritic plaque formation and microglial activation in a transgenic model of Alzheimer’s disease
Cell Death Dis

Verkhratsky A, Rodríguez JJ (2010)
The Achilles heel of γ-secretase: Can we contain Alzheimer’s disease by reducing synthesis of β-amyloid?
Acta Pharmacologica Sinica

C.J. Peddie, H.A. Davies, F.M. Colyer, M.G. Stewart and J.J Rodríguez. (2010)
A subpopulation of serotonin (1B) receptors colocalize with AMPA receptor subunit GluR2 in the hippocampal dentate gyrus
Neurosci Lett.

Heneka MT, Rodríguez JJ, Verkhratsky A. (2010)
Neuroglia in neurodegeneration.
Brain Res Rev.

Nedergaard M, Rodríguez JJ, Verkhratsky A. (2010)
Glial calcium and diseases of the nervous system.
Cell Calcium

Olabarria M, Noristani HN, Verkhratsky A, Rodríguez JJ. (2010)
Concomitant astroglial atrophy and astrogliosis in a triple transgenic animal model of Alzheimer's disease.
Glia

Noristani HN, Olabarria M, Verkhratsky A, Rodríguez JJ. (2010)
Serotonin fibre sprouting and increase in serotonin transporter immunoreactivity in the CA1 area of hippocampus in a triple transgenic mouse model of Alzheimer's disease.
Eur J Neurosci

Verkhratsky A, Olabarria M, Noristani HN, Yeh CY, Rodriguez JJ. (2010)
Astrocytes in Alzheimer's disease.
Neurotherapeutics

In press

  • J.J. Rodriguez, A. Verkhratsky (2012)
    Type: chapters
    Book: Research Progress in Alzheimer’s Disease and Dementia
    Chapter: Neuroglial Integrity and Neurodegenerative Disorders
    Page numbers: -
    ISBN: - | New York | Editors:
  • Rodriguez J.J., Matute C. and Verkhratsky A. (2011)
    Type: chapters
    Book: Astrocytes: Wiring the brain
    Chapter: Neuroglia in Alzheimer's Disease
    Page numbers: -
    ISBN: - | Florida, USA | Editors:

Doctoral dissertations

  • Pathophysiological adaptation and role of astrocytes in Alzheimer's disease: a longitudinal analysis in a triple transgenic mouse model
    2008 - 2011
    The University of Manchester
    Markel Olabarria Larizgoitia

Courses given

  • 2011
    Neuroglial alterations and plasticity during the progression of Alzheimer´s disease”. Instituto de Biología y Medicina Experimental (CONICET). Buenos Aires, Argentina.
  • 2011
    “Neurogenic impairments and recovery in Alzheimer´s disease: a new therapeutical target?”. Departamento de Química Biológica, Fac de Ciencias Exactas y Naturales, Universidad de Buenos Aires. Buenos Aires, Argentina.
  • 2011
    “Neuronal and Neuroglial changes during the progresión of Alzheimer´s disease: pathological vs. plastic potential ”. Glia Day. Center for Translational Neuromedicine. The University of Rochester. NY, USA.
  • 2011
    Neurogenic changes during the progression of Alzheimer´s disease and its therapeutical potential”. Biodonostia. San Sebastian
  • 2011
    “Neuroglial alterations during the progression of Alzheimer's disease”. The Netherlands Institute for Neuroscience. Amsterdam, Netherlands.
  • 2010
    “Astroglial atrophy and microglial recruitment during the progression of Alzheimer's disease”. Birmingham, AL. USA.
  • 2010
    “Neuronal and Glial alterations and interactions during the progression of Alzheimer’s disease”. Biophysics Society. Bilbao.
  • 2010
    “Differential neurogenic impairment during the progression of Alzheimer’s disease”. Institute for Neurosciences. Montpellier, France
  • 2010
    “New players in the Progression of Alzheimer’s disease”. San Sebastian Hospital. San Sebastian.

Congresses, Proceedings & Scientific meetings

  • Alzheimer's disease associated neuroglia and neurogenic alterations. J.J. Rodríguez, A. Verkhratsky.
    41st Annual Meeting of the Society for Neuroscience. (2011) Congress
    Washington DC, USA (Poster)
  • Neurogenesis: A New Key Player in the Progression of Alzheimer’s Disease and its Therapeutics. Rodríguez J.J, Yeh CY, Olabarria M., Noristani H.N., Verkhratsky A.
    11th Alzheimer’s Association International Conference on Alzheimer’s Disease (2011) Congress
    Paris (Poster)
  • Reflexiones en Neurociencia: Integración y Desintegración del Cerebro / Reflexions in Neuroscience: Integration and Desintegration of the Brain.. J.J. Rodríguez, A. Verkhratsky.
    Reflexiones en Neurociencia: Integración y Desintegración del Cerebro / Reflexions in Neuroscience: Integration and Desintegration of the Brain. (2011) Congress
    Bilbao (Organization and management)
  • Astrocytes and Alzheimer’s disease. J.J. Rodríguez
    10th European meeting on glial cells in health and disease. (2011) Congress
    Prague, Czech Republic. (Invited talk)
  • Neuroglial role in the development and progress of Alzheimer´s disease: from God to Evil. J.J. Rodríguez
    10th European meeting on glial cells in health and disease (2011) Congress
    Prague, Czech Republic. (Invited talk)
  • Calcium signalling in neuroglia. A. Verkhratsky, J.J. Rodríguez, V. Parpura
    Joint Congress of FEPS and Turkish Society of Physiological Science (2011) Congress
    Istanbul, Turkey (Invited talk)
  • Chemical transmission in neuronal-glial networks. A. Verkhratsky, J.J. Rodríguez, V. Parpura
    Joint Congress of FEPS and Turkish Society of Physiological Science (2011) Congress
    Istanbul, Turkey (Invited talk)
  • The forgotten and dark side of Alzheimer´s Disease: Neuroglial Pathology. J.J. Rodríguez
    Joint Congress of FEPS and Turkish Society of Physiological Science (2011) Congress
    Istanbul, Turkey (Invited talk)
  • Neuroglial alterations in neurodegeneration. J.J. Rodríguez
    Reflexiones en Neurociencia: Integración y Desintegración del Cerebro / Reflexions in Neuroscience: Integration and Disintegration of the Brain (2011) Congress
    Bilbao (Talk)
  • Living with Alzheimer’s and neuroscience: Transfer of the basic findings to the clinical and care application in the treatment of Alzheimer's disease. J.J. Rodríguez
    Reflexiones en Neurociencia: Integración y Desintegración del Cerebro / Reflexions in Neuroscience: Integration and Desintegration of the Brain. (2011) Congress
    Bilbao (Talk)
  • Living with Alzheimer’s and neuroscience: Fundamental aspects of basic research into Alzheimer’s disease. J.J. Rodríguez
    Reflexiones en Neurociencia: Integración y Desintegración del Cerebro / Reflexions in Neuroscience: Integration and Desintegration of the Brain. (2011) Congress
    Bilbao (Talk)
  • New key players in the progression of Alzheimer's disease and its therapeutics. J.J. Rodríguez
    BIT's 2nd Annual World Congress of NeuroTalk (2011) Congress
    Dalian, China (Invited talk)
  • Ionotropic receptors in astroglia. J.J. Rodríguez
    Joint Conference of Czech and Slovak Neuroscience Societies (2011) Congress
    Smolenice, Slovakia (Talk)
  • Neuroglial and neurogenic alterations during the progression of Alzheimer’s disease. J.J. Rodríguez
    Joint Conference of Czech and Slovak Neuroscience Societies (2011) Congress
    Smolenice, Slovakia (Talk)
  • The dark side of Alzheimer’s disease: might be the light at the end of the tunnel?. J.J. Rodríguez
    Biogune/Ikerbasque Annual Meeting (2010) Congress
    Bilbao (Talk)
  • Increased hippocampal serotonin transporter protein in a triple trangenic model of Alzhemier’s disease. Noristani H., Olabarria M., Verkhratsky A., Rodríguez J.J.
    39th Annual Meeting of the Society for Neuroscience (2009) Congress
    Society for Neuroscience. Chicago. USA (Poster)
 
Release performed by ecmware