Ikerbasque. Basque Foundation for Science

Cavanillas M.L., Fernandez O., Comabella M., Alcina A., Fedetz M., Izquierdo G., Lucas M., Cénit M.C., Arroyo R., Vandenbroeck K., Alloza I., García-Barcina M., Antigüedad A., Leyva L., López-Gómez C., Olascoaga J., Otaegui D., Blanco Y., Saiz A., Mo (2011)
Replication of top markers of a genome-wide association study in multiple sclerosis in Spain
Genes and Immunity

Vandenbroeck K., Alloza I., Swaminathan B., Antigüedad A., Otaegui D., Olascoaga J., García Barcina M., de las Heras V., Bartolomé M., Fernández-Arquero M., Arroyo R., Alvarez-Lafuente R., Cénit M.C. and Urcelay E. (2011)
Validation of IRF5 as multiple sclerosis risk gene: putative role in interferon beta therapy and human herpes virus 6 infection
Genes and Immunity

McLaughlin M. and Vandenbroeck K. (2011)
The endoplasmic reticulum protein folding factory and its chaperones: new targets for drug discovery?
British Journal of Pharmacology

Comabella M. and Vandenbroeck K. (2011)
Pharmacogenomics and multiple sclerosis: moving towards individualized medicine
Current Neurology and Neuroscience Reports

Malhotra S., Morcillo-Suárez C., Brassat D., Goertsches R., Urcelay E., Fernández O., Drulovic J., García-Merino A., Martinelli Boneschi F., Chan A., Vandenbroeck K., Navarro A., Bustamante M.F., Río J., Oksenberg J., Montalban X. et al. (2011)
IL28B polymorphisms are not associated with the response to interferon-beta in multiple sclerosis
Journal of Neuroimmunology

McLaughlin M., Alloza I., Quoc P.H., Scott C.J., Hirabayashi Y. and Vandenbroeck K. (2010)
Inhibition of secretion of interleukin (IL)-12/IL-23 family cytokines by 4-trifluoromethylcelecoxib is coupled to degradation via the endoplasmic reticulum stress protein HERP
The Journal of Biological Chemistry

Alcina A.*, Vandenbroeck K.*, Otaegui D.*, Saiz A., Gonzalez J.R., Fernandez O., Cavanillas M.L., Cénit M.C., Arroyo R., Alloza I., García-Barcina M., Antigüedad A., Leyva L., Izquierdo G., Lucas M., Fedetz M., Pinto-Medel M.J., Olascoaga J., Blanco Y (2010)
The autoimmune-disease associated KIF5A, CD226 and SH2B3 gene variants confer susceptibility for multiple sclerosis
Genes and Immunity

Swaminathan B., Matesanz F., Cavanillas M.L., Alloza I., Otaegui D., Olascoaga J., Cénit M.C., de la Heras V., García Barcina M., Arroyo R., Alcina A., Fernandez O., Antigüedad A., Urcelay E. and Vandenbroeck K. (2010)
Validation of the CD6 and TNFRSF1A loci as risk factors for multiple sclerosis in Spain
Journal of Neuroimmunology

Vandenbroeck K. and Comabella M. (2010)
Single-nucleotide polymorphisms in response to interferon-beta therapy in multiple sclerosis
Journal of Interferon & Cytokine Research

Vandenbroeck K., Urcelay E. and Comabella M. (2010)
Interferon-beta pharmacogenomics in multiple sclerosis
Pharmacogenomics

Burkart V., Siegenthaler R.K., Blasius E., Vandenbroeck K., Alloza I., Fingberg W., Schoot N.C., Christen P. and Kolb H. (2010)
High affinity binding of hydrophobic and autoantigenic regions of proinsulin to the 70 kDa chaperone, DnaK.
BMC Biochemistry

O'Doherty C., Alloza I., Rooney M. and Vandenbroeck K. (2009)
IL7RA polymorphisms and chronic inflammatory arthropathies
Tissue Antigens

Vandenbroeck K., Comabella M., Tolosa E., Goertsches R., Brassat D., Hintzen R., Infante–Duarte C., Favorov A., Escorza S., Palacios R., Oksenberg J.R. and Villoslada P (2009)
Special Report – United Europeans for development of pharmacogenomics in multiple sclerosis network
Pharmacogenomics

O’Doherty C., Favorov A., Heggarty S., Graham C., Favorova O., Ochs M., Hawkins S., Hutchinson M., O’Rourke K. and Vandenbroeck K. (2009)
Genetic polymorphisms, their allele combinations and interferon-β treatment response in Irish multiple sclerosis patients
Pharmacogenomics

Kantarci O.H., Hebrink D.D., Schaefer-Klein J., Sun Y., Achenbach S., Atkinson E.J., Heggarty S., Cotleur A.C., de Andrade M., Vandenbroeck K., Pelfrey C.M. and Weinshenker B.G. (2008)
Interferon gamma allelic variants: sex-biased multiple sclerosis susceptibility and gene expression
Archives of Neurology

Hawwa A.F., Millership J.S., Collier P.S., Vandenbroeck K., McCarthy A., Dempsey S., Cairns C., Collins J., Rodgers C. and McElnay J.C (2008)
Pharmacogenomic studies of the anticancer and immunosuppressive thiopurines mercaptopurine and azathioprine
British Journal of Pharmacology

Booth D, Heard R., Stewart G., Rioux J., Daly M., Vandenbroeck K., Barcellos L., Sawcer S., Oksenberg J. and others (IMSGC) (2008)
Refining genetic associations in multiple sclerosis
Lancet Neurology

O’Doherty C., Kantarci O.H. and Vandenbroeck K. (2008)
IL7RA polymorphisms and susceptibility to multiple sclerosis
New England Journal of Medicine

Paunović V., Carroll H.P., Vandenbroeck K. and Gadina M. (2008)
Crossed signals: the role of interleukin (IL)-12, -17, -23, and -27 in autoimmunity
Rheumatology

Vandenbroeck K. and Matute C. (2008)
Pharmacogenomics of the response to IFN-β in multiple sclerosis: ramifications from the first genome-wide screen
Pharmacogenomics

Tsareva E.Y., Kulakova O.G., Boyko A.N., Shchur S.G., Lvovs D., Favorov A.V., Vandenbroeck K. and Favorova O. (2012)
Allelic combinations of immune response genes associated with glatiramer acetate treatment response in Russian multiple sclerosis patients
Pharmacogenomics

Vandenbroeck K., Alvarez J., Swaminathan B., Alloza I., Matesanz F., Ucelay E., Comabella M., Alcina A., Fedetz M., Ortiz M.A., Izquierdo G., Fernández O., Rodriguez-Ezpeleta N., Matute C., Cailler S., Arroyo R., Montalban X., Oksenberg J.R., Antigüedad (2012)
A cytokine gene screen uncovers SOCS1 as genetic risk factor for multiple sclerosis
Genes and Immunity

Varadé J., Comabella M., Ortiz M.A., [....] , Montalban X., Vandenbroeck K. and Urcelay E. (2012)
Replication study of ten genes showing evidence for association with multiple sclerosis: validation of TMEM39A, IL12B and CLBL genes
Multiple Sclerosis Journal

Alloza I., Otaegui D., Lopez de Lapuente A., Antigüedad A., [….] , Vandenbroeck K. (2012)
ANKRD55 and DHCR7 are novel multiple sclerosis risk genes
Genes and Immunity

Cantó E, Reverter F, Morcillo-Suárez C, Matesanz F, Fernández O, Vandenbroeck K, Rodriguez-Antigüedad A, Urcelay E, Otaegui D, Olascoaga J, Saiz A, Navarro A, Sanchez A et al. (2012)
Chitinase 3-like 1 plasma levels are increased in patients with progressive forms of multiple sclerosis
Multiple Sclerosis Journal