Ainara Castellanos

Ikerbasque Research Fellow, UPV/EHU

Currently works at at the Department of Genetics, Physical Anthropology and Animal Physiology of University of the Basque Country

Research line:

Functional genetics of complex immune disorders.

Research experience at BioCruces Research Institute, University of Tampere (Finland) and Columbia University (US)

Dr in Biology (2010) from University of the Basque Country (UPV-EHU)

2021

Article / Gluten-induced RNA methylation changes regulate intestinal inflammation via allele-specific XPO1 translation in epithelial cells

Gut

Olazagoitia-Garmendia, A.; Zhang, L.; Mera, P.; Godbout, J.K.; Sebastian-Delacruz, M.; Garcia, I.; Mendoza, L.M.; Huerta, A.; Irastorza, I.; Bhagat, G.; Green, P.H.; Herrero, L.; Serra, D.; Rodriguez, J.A.; Verdu, E.F.; He, C.; Bilbao, J.R.; Castellanos-Rubio, A. (2021)

Review / The role of lncrnas in gene expression regulation through mRNA stabilization

Non-coding RNA

Sebastian-Delacruz, M.; Gonzalez-Moro, I.; Olazagoitia-Garmendia, A.; Castellanos-Rubio, A.; Santin, I. (2021)

2020

Article / The T1D-associated lncRNA Lnc13 modulates human pancreatic ? cell inflammation by allele-specific stabilization of STAT1 mRNA.

PNAS

Gonzalez-Moro I, Olazagoitia-Garmendia A, Colli ML, Cobo-Vuilleumier N, Postler TS, Marselli L, Marchetti P, Ghosh S, Gauthier BR, Eizirik DL, Castellanos-Rubio A, Santin I. (2020)

Article / Highly Reproducible Hyperthermia Response in Water, Agar, and Cellular Environment by Discretely PEGylated Magnetite Nanoparticles

ACS Applied Materials and Interfaces

Castellanos-Rubio, I.; Rodrigo, I.; Olazagoitia-Garmendia, A.; Arriortua, O.; Gil De Muro, I.; Garitaonandia, J.S.; Bilbao, J.R.; Fdez-Gubieda, M.L.; Plazaola, F.; Orue, I.; Castellanos-Rubio, A.; Insausti, M. (2020)

Article / The T1D-associated lncRNA Lnc13 modulates human pancreatic β cell inflammation by allele-specific stabilization of STAT1 mRNA

Proceedings of the National Academy of Sciences of the United States of America

Gonzalez-Moro, I.; Olazagoitia-Garmendia, A.; Colli, M.L.; Cobo-Vuilleumier, N.; Postler, T.S.; Marselli, L.; Marchetti, P.; Ghosh, S.; Gauthier, B.R.; Eizirik, D.L.; Castellanos-Rubio, A.; Santin, I. (2020)

2019

Article / MAGI2 Gene Region and Celiac Disease

Frontiers in Nutrition

Jauregi-Miguel, A.; Santin, I.; Garcia-Etxebarria, K.; Olazagoitia-Garmendia, A.; Romero-Garmendia, I.; Sebastian-delaCruz, M.; Irastorza, I.; Castellanos-Rubio, A.; Bilbao, J.R. (2019)

Article / A novel RT-QPCR-based assay for the relative quantification of residue specific m6A RNA methylation

Scientific Reports

Castellanos-Rubio, A.; Santin, I.; Olazagoitia-Garmendia, A.; Romero-Garmendia, I.; Jauregi-Miguel, A.; Legarda, M.; Bilbao, J.R. (2019)

2019

FUNCTIONAL CHARACTERIZATION OF A lncRNA IN THE AUTOIMMUNE DISEASE-ASSOCIATED RGS1 REGION

Ane Olazagoitia-Garmendia, Nora Fernandez-Jimenez, Jose Ramon Bilbao and Ainara Castellanos-Rubio

The T1D-associated lncRNA Lnc13 modulates pancreatic ? cell inflammation by allele-specific stabilization of STAT1 and STAT2 mRNA.

Itziar Gonzalez-Moro, Ane Olazagoitia-Garmendia, Ainara Castellanos-Rubio, Izortze Santin.

Functional study of the rs6822844 SNP associated with risk to celiac disease in intestinal cells

Maialen Sebastian-delaCruz, Ane Olazagoitia-Garmendia, Irati Romero-Garmendia, Maria Legarda, Carlos Tutau, Iñaki Irastorza, Ainara Castellanos-Rubio, Jose Ramon Bilbao

LOC339803 lncRNA mediates susceptibility to intestinal inflammation by allele-specific methylation-dependent gene expression regulation

Ane Olazagoitia-Garmendia, Maialen Sebastian-delaCruz, Iñaki Irastorza, Izortze Santin, Jose Ramón Bilbao and Ainara Castellanos-Rubio

LOC339803 lncRNA mediates susceptibility to immune-diseases by tissue-dependent allele-specific gene expression regulation

Ainara Castellanos-Rubio, Ane Olazagoitia-Garmendia, Izortze Santin, Iñaki Irastorza, Javier Meana and Jose Ramón Bilbao