Research line:
Structural MicrobiologyPrevious research experience at Imperial College London and Durham University (UK).
Ikerbasque Fellow
PhD in Chemistry from the University of Birmingham (UK).
2018
Regulation of Human Hsc70 ATPase and Chaperone Activities by Apg2: Role of the Acidic Subdomain
J Mol Biol
Cabrera Y, Dublang L, Fernández-Higuero JA, Albesa-Jové D, Lucas M, Viguera AR, Guerin ME, Vilar JMG, Muga A, Moro F (2018)
The Molecular Mechanism of Substrate Recognition and Catalysis of the Membrane Acyltransferase PatA from Mycobacteria
ACS Chemical Biology
Montse Tersa, Lluís Raich, David Albesa-Jové, Beatriz Trastoy, Jacques Prandi, Martine Gilleron, Carme Rovira, Marcelo E Guerin (2018)
2017
Structural Snapshots and Loop Dynamics along the Catalytic Cycle of Glycosyltransferase GpgS
Structure
David Albesa-Jové, Javier Romero-García, Enea Sancho-Vaello, F-Xabier Contreras, Ane Rodrigo-Unzueta, Natalia Comino, Ana Carreras-González, Pedro Arrasate, Saioa Urresti, Xevi Biarnés, Antoni Planas, Marcelo E Guerin (2017)
The antibacterial prodrug activator Rv2466c is a mycothiol-dependent reductase in the oxidative stress response of Mycobacterium tuberculosis
Journal of Biological Chemistry
Leonardo Astolfi Rosado, Khadija Wahni, Giulia Degiacomi, Brandan Pedre, David Young, G Alfonso, Francesca Boldrin, Edo Martens, Laura Marcos-Pascual, Enea Sancho-Vaello, David Albesa-Jové, Roberta Provvedi, Charlotte Martin, Vadim Makarov, Wim Versées, G (2017)
Structural Snapshots of alpha-1, 3-Galactosyltransferase with Native Substrates: Insight into the Catalytic Mechanism of Retaining Glycosyltransferases
Angewandte Chemie
David Albesa-Jové*, M Ángela Sainz-Polo, Alberto Marina, Marcelo E Guerin* (corresponding author) (2017)
Structural basis of phosphatidylinositol mannosides biosynthesis in mycobacteria
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids
Enea Sancho-Vaello, David Albesa-Jové, Ane Rodrigo-Unzueta, Marcelo E Guerin (2017)
2016
Structural basis for selective recognition of acyl chains by the membrane-associated acyltransferase PatA
Nature Communications
David Albesa-Jové, Zuzana Svetlíková, Montse Tersa, Enea Sancho-Vaello, Ana Carreras-González, Pascal Bonnet, Pedro Arrasate, Ander Eguskiza, Shiva K Angala, Javier O Cifuente, Jana Korduláková, Mary Jackson, Katarína Mikušová, Marcelo E Guerin (2016)
TssA forms a gp6-like ring attached to the type VI secretion sheath
The EMBO Journal
Sara Planamente, Osman Salih, Eleni Manoli, David Albesa?Jové, Paul S Freemont, Alain Filloux (2016)
Structural Basis of Glycogen Biosynthesis Regulation in Bacteria
Structure
Javier O Cifuente, Natalia Comino, Julene Madariaga-Marcos, Sonia López-Fernández, Mikel García-Alija, Jon Agirre, David Albesa-Jové*, Marcelo E Guerin* (Corresponding authors) (2016)
The conformational plasticity of glycosyltransferases
Current Opinion in Structural Biology
David Albesa-Jové, Marcelo E Guerin (2016)
2015
Secondary structure reshuffling modulates glycosyltransferase function at the membrane
Nature chemical biology
David Giganti, David Albesa-Jové, Saioa Urresti, Ane Rodrigo-Unzueta, Mariano A Martínez, Natalia Comino, Nathalie Barilone, Marco Bellinzoni, Alexandre Chenal, Marcelo E Guerin, Pedro M Alzari (2015)
A Native Ternary Complex Trapped in a Crystal Reveals the Catalytic Mechanism of a Retaining Glycosyltransferase
Angewandte Chemie
David Albesa-Jové, Fernanda Mendoza, Ane Rodrigo-Unzueta, Fernando Gomollón-Bel, Javier O Cifuente, Saioa Urresti, Natalia Comino, Hansel Gómez, Javier Romero-García, José M Lluch, Enea Sancho?Vaello, Xevi Biarnés, Antoni Planas, Pedro Merino, Laura Masgr (2015)
The redox state regulates the conformation of Rv2466c to activate the antitubercular prodrug TP053
Journal of Biological Chemistry
David Albesa-Jové, Natalia Comino, Montse Tersa, Elisabeth Mohorko, Saioa Urresti, Elisa Dainese, Laurent R Chiarelli, Maria Rosalia Pasca, Riccardo Manganelli, Vadim Makarov, Giovanna Riccardi, Dmitri I Svergun, Rudi Glockshuber, Marcelo E Guerin (2015)
2014
Iridium-catalyzed C–H borylation of pyridines
Organic & Biomolecular Chemistry
Sadler, Scott A. Tajuddin, Hazmi Mkhalid, Ibraheem A. I. Batsanov, Andrei S. Albesa-Jové, David Cheung, Man Sing Maxwell, Aoife C. Shukla, Lena Roberts, Bryan Blakemore, David C. Lin, Zhenyang Marder, Todd B. Steel, Patrick G. (2014)
Structure–function relationships of membrane-associated GT-B glycosyltransferases
Glycobiology
David Albesa-Jové, David Giganti, Mary Jackson, Pedro M Alzari, Marcelo E Guerin (2014)
Rv2466c Mediates the Activation of TP053 To Kill Replicating and Non-replicating Mycobacterium tuberculosis
ACS chemical biology
David Albesa-Jové, Laurent R Chiarelli, Vadim Makarov, Maria Rosalia Pasca, Saioa Urresti, Giorgia Mori, Elena Salina, Anthony Vocat, Natalia Comino, Elisabeth Mohorko, Svetlana Ryabova, Bernhard Pfieiffer, Ana Luisa de Jesus Lopes Ribeiro, Ane Rodrigo-U (2014)
Structural basis of chitin oligosaccharide deacetylation
Angewandte Chemie International Edition
Eduardo Andrés*, David Albesa-Jové*, Xevi Biarnés, Bruno M Moerschbacher, Marcelo E Guerin, Antoni Planas (*equal contribution) (2014)
2013
Conformational Plasticity of the Essential Membrane-associated Mannosyltransferase PimA from Mycobacteria
Journal of Biological Chemistry
David Giganti, Jorge Alegre-Cebollada, Saioa Urresti, David Albesa-Jové, Ane Rodrigo-Unzueta, Natalia Comino, Michael Kachala, Sonia López-Fernández, Dmitri I Svergun, Julio M Fernández, Marcelo E Guerin (2013)
2012
Structural Versatility of Pyrene-2-(4, 4, 5, 5-tetramethyl-[1, 3, 2] dioxaborolane) and Pyrene-2, 7-bis (4, 4, 5, 5-tetramethyl-[1, 3, 2] dioxaborolane)
Crystal Growth & Design
Andrei S Batsanov, Judith AK Howard, David Albesa-Jové, Jonathan C Collings, Zhiqiang Liu, Ibraheem AI Mkhalid, Marie-He?le?ne Thibault, Todd B Marder (2012)
Mechanistic insights into the retaining glucosyl-3-phosphoglycerate synthase from mycobacteria
Journal of Biological Chemistry
Saioa Urresti*, David Albesa-Jové*, Francis Schaeffer, Ha T Pham, Devinder Kaur, Petra Gest, Mark J van der Woerd, Ana Carreras-González, Sonia López-Fernández, Pedro M Alzari, Patrick J Brennan, Mary Jackson, Marcelo E Guerin (*equal contribution) (2012)
2011
The electronic structures of diruthenium complexes containing an oligo (phenylene ethynylene) bridging ligand, and some related molecular structures Authors
Dalton Trans.
Wan M Khairul, Mark A Fox, Phil A Schauer, Dmitry S Yufit, David Albesa-Jové, Judith AK Howard, Paul J Low (2011)
Type VI Secretion System in Pseudomonas aeruginosa
Journal of Biological Chemistry
Abderrahman Hachani, Nadine S Lossi, Alexander Hamilton, Cerith Jones, Sophie Bleves, David Albesa-Jové, Alain Filloux (2011)
2010
Four distinct structural domains in Clostridium difficile toxin B visualized using SAXS
Journal of molecular biology
David Albesa-Jové, Thomas Bertrand, Elisabeth P Carpenter, Gemma V Swain, Jenson Lim, Jiancheng Zhang, Lesley F Haire, Nishi Vasisht, Veit Braun, Anton Lange, Christoph von Eichel-Streiber, Dmitri I Svergun, Neil F Fairweather, Katherine A Brown (2010)
2009
Structural insights into the molecular organization of the S-layer from Clostridium difficile
Molecular microbiology
Robert P Fagan, David Albesa-Jové, Omar Qazi, Dmitri I Svergun, Katherine A Brown, Neil F Fairweather (2009)
Syntheses, structures, two-photon absorption cross-sections and computed second hyperpolarisabilities of quadrupolar A–pi–A systems containing E-dimesitylborylethenyl acceptors
J. Mater. Chem.
Christopher D Entwistle, Jonathan C Collings, Andreas Steffen, Lars-Olof Pålsson, Andrew Beeby, David Albesa-Jové, Jacquelyn M Burke, Andrei S Batsanov, Judith AK Howard, Jackie A Mosely, Suk-Yue Poon, Wai-Yeung Wong, Fatima Ibersiene, Sofiane Fathallah, (2009)
2008
A Solid-State Dehydration Process Associated with a Significant Change in the Topology of Dihydrogen Phosphate Chains, Established from Powder X-ray Diffraction
Crystal Growth & Design
Albesa-Jové, David Pan, Zhigang Harris, Kenneth D. M. Uekusa, Hidehiro (2008)
Ruthenium complexes of C, C'-bis (ethynyl) carboranes: An investigation of electronic interactions mediated by spherical pseudo-aromatic spacers
Journal of the American Chemical Society
Mark A Fox, Rachel L Roberts, Thomas E Baines, Boris Le Guennic, Jean-François Halet, František Hartl, Dmitri S Yufit, David Albesa-Jové, Judith AK Howard, J Paul (2008)
2006
Ir-Catalyzed Borylation of C-H Bonds in N-Containing Heterocycles: Regioselectivity in the Synthesis of Heteroaryl Boronate Esters
Angewandte Chemie International Edition
Ibraheem AI Mkhalid, David N Coventry, David Albesa-Jove, Andrei S Batsanov, Judith AK Howard, Robin N Perutz, Todd B Marder (2006)
Synthesis, Crystal Structures, Linear and Nonlinear Optical Properties, and Theoretical Studies of (p-R-Phenyl)-,(p-R-Phenylethynyl)-, and (E)-[2-(p-R-Phenyl) ethenyl] dimesitylboranes and Related Compounds
Chemistry-A European Journal
Zheng Yuan, Christopher D Entwistle, Jonathan C Collings, David Albesa-Jové, Andrei S Batsanov, Judith AK Howard, Nicholas J Taylor, Hanns Martin Kaiser, Dieter E Kaufmann, Suk-Yue Poon, Wai-Yeung Wong, Christophe Jardin, Sofiane Fathallah, Abdou Boucekki (2006)
2005
Synthesis, optical properties, crystal structures and phase behaviour of symmetric, conjugated ethynylarene-based rigid rods with terminal carboxylate groups
Journal of Materials Chemistry
Fasina, Tolulope M Collings, Jonathan C Burke, Jacqueline M Batsanov, Andrei S Ward, Richard M Albesa-Jové, David Porrès, Laurent Beeby, Andrew Howard, Judith A.K. Scott, Andrew J Clegg, William Watt, Stephen W. Viney, Christopher Marder, Todd B. (2005)
