David Albesa-Jové

Ikerbasque Research Associate, Biofisika Institute

Conoce a David

Ikerbasque Research Associate at Biofisika Institute.

Research line:

Structural Microbiology.

Previous research experience at CIC bioGUNE (ES), the Imperial College London and Durham University (UK).

PhD in Chemistry from the University of Birmingham (UK).

Publicaciones

2020

Structural insights into Pseudomonas aeruginosa Type six secretion system exported effector 8

Journal of Structural Biology

Amaia González-Magaña, M Ángela Sainz-Polo, Gabriela Pretre, Retina Çapuni, María Lucas, Jon Altuna, Itxaso Montánchez, Paola Fucini, David Albesa-Jové (2020)

Dissecting the Structural and Chemical Determinants of the “Open-to-Closed” Motion in the Mannosyltransferase PimA from Mycobacteria

Biochemistry

Ane Rodrigo-Unzueta, Mattia Ghirardello, Saioa Urresti, Ignacio Delso, David Giganti, Itxaso Anso, Beatriz Trastoy, Natalia Comino, Montse Tersa, Cecilia D’Angelo, Javier O Cifuente, Alberto Marina, Jobst Liebau, Lena Ma?ler, Alexandre Chenal, David Albes (2020)

The allosteric control mechanism of bacterial glycogen biosynthesis disclosed by cryoEM

Current Research in Structural Biology

Javier O Cifuente, Natalia Comino, Cecilia D’Angelo, Alberto Marina, David Gil-Carton, David Albesa-Jové, Marcelo E Guerin (2020)

2019

Structure-function relationships underlying the dual N-acetylmuramic and N-acetylglucosamine specificities of the bacterial peptidoglycan deacetylase PdaC

Journal of Biological Chemistry

Laia Grifoll-Romero, María Angela Sainz-Polo, David Albesa-Jové, Marcelo E Guerin, Xevi Biarnés, Antoni Planas (2019)

Quick-soaking of crystals reveals unprecedented insights into the catalytic mechanism of glycosyltransferases.

Methods in Enzymology

David Albesa-Jové, Javier O. Cifuente, Beatriz Trastoy, Marcelo E. Guerin (2019)

Regulation of Human Hsc70 ATPase and Chaperone Activities by Apg2: Role of the Acidic Subdomain

J Mol Biol

Cabrera Y, Dublang L, Fernández-Higuero JA, Albesa-Jové D, Lucas M, Viguera AR, Guerin ME, Vilar JMG, Muga A, Moro F (2019)

2018

The Molecular Mechanism of Substrate Recognition and Catalysis of the Membrane Acyltransferase PatA from Mycobacteria

ACS Chemical Biology

Montse Tersa, Lluís Raich, David Albesa-Jové, Beatriz Trastoy, Jacques Prandi, Martine Gilleron, Carme Rovira, Marcelo E Guerin (2018)

2017

Structural Snapshots and Loop Dynamics along the Catalytic Cycle of Glycosyltransferase GpgS

Structure

David Albesa-Jové, Javier Romero-García, Enea Sancho-Vaello, F-Xabier Contreras, Ane Rodrigo-Unzueta, Natalia Comino, Ana Carreras-González, Pedro Arrasate, Saioa Urresti, Xevi Biarnés, Antoni Planas, Marcelo E Guerin (2017)

The antibacterial prodrug activator Rv2466c is a mycothiol-dependent reductase in the oxidative stress response of Mycobacterium tuberculosis

Journal of Biological Chemistry

Leonardo Astolfi Rosado, Khadija Wahni, Giulia Degiacomi, Brandan Pedre, David Young, G Alfonso, Francesca Boldrin, Edo Martens, Laura Marcos-Pascual, Enea Sancho-Vaello, David Albesa-Jové, Roberta Provvedi, Charlotte Martin, Vadim Makarov, Wim Versées, G (2017)

Structural Snapshots of alpha-1, 3-Galactosyltransferase with Native Substrates: Insight into the Catalytic Mechanism of Retaining Glycosyltransferases

Angewandte Chemie

David Albesa-Jové*, M Ángela Sainz-Polo, Alberto Marina, Marcelo E Guerin* (corresponding author) (2017)

Structural basis of phosphatidylinositol mannosides biosynthesis in mycobacteria

Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids

Enea Sancho-Vaello, David Albesa-Jové, Ane Rodrigo-Unzueta, Marcelo E Guerin (2017)

2016

Structural basis for selective recognition of acyl chains by the membrane-associated acyltransferase PatA

Nature Communications

David Albesa-Jové, Zuzana Svetlíková, Montse Tersa, Enea Sancho-Vaello, Ana Carreras-González, Pascal Bonnet, Pedro Arrasate, Ander Eguskiza, Shiva K Angala, Javier O Cifuente, Jana Korduláková, Mary Jackson, Katarína Mikušová, Marcelo E Guerin (2016)

TssA forms a gp6-like ring attached to the type VI secretion sheath

The EMBO Journal

Sara Planamente, Osman Salih, Eleni Manoli, David Albesa?Jové, Paul S Freemont, Alain Filloux (2016)

Structural Basis of Glycogen Biosynthesis Regulation in Bacteria

Structure

Javier O Cifuente, Natalia Comino, Julene Madariaga-Marcos, Sonia López-Fernández, Mikel García-Alija, Jon Agirre, David Albesa-Jové*, Marcelo E Guerin* (Corresponding authors) (2016)

The conformational plasticity of glycosyltransferases

Current Opinion in Structural Biology

David Albesa-Jové, Marcelo E Guerin (2016)

2015

Secondary structure reshuffling modulates glycosyltransferase function at the membrane

Nature chemical biology

David Giganti, David Albesa-Jové, Saioa Urresti, Ane Rodrigo-Unzueta, Mariano A Martínez, Natalia Comino, Nathalie Barilone, Marco Bellinzoni, Alexandre Chenal, Marcelo E Guerin, Pedro M Alzari (2015)

A Native Ternary Complex Trapped in a Crystal Reveals the Catalytic Mechanism of a Retaining Glycosyltransferase

Angewandte Chemie

David Albesa-Jové, Fernanda Mendoza, Ane Rodrigo-Unzueta, Fernando Gomollón-Bel, Javier O Cifuente, Saioa Urresti, Natalia Comino, Hansel Gómez, Javier Romero-García, José M Lluch, Enea Sancho-Vaello, Xevi Biarnés, Antoni Planas, Pedro Merino, Laura Masgr (2015)

The redox state regulates the conformation of Rv2466c to activate the antitubercular prodrug TP053

Journal of Biological Chemistry

David Albesa-Jové, Natalia Comino, Montse Tersa, Elisabeth Mohorko, Saioa Urresti, Elisa Dainese, Laurent R Chiarelli, Maria Rosalia Pasca, Riccardo Manganelli, Vadim Makarov, Giovanna Riccardi, Dmitri I Svergun, Rudi Glockshuber, Marcelo E Guerin (2015)

2014

Iridium-catalyzed C–H borylation of pyridines

Organic & Biomolecular Chemistry

Sadler, Scott A. Tajuddin, Hazmi Mkhalid, Ibraheem A. I. Batsanov, Andrei S. Albesa-Jové, David Cheung, Man Sing Maxwell, Aoife C. Shukla, Lena Roberts, Bryan Blakemore, David C. Lin, Zhenyang Marder, Todd B. Steel, Patrick G. (2014)

Structure–function relationships of membrane-associated GT-B glycosyltransferases

Glycobiology

David Albesa-Jové, David Giganti, Mary Jackson, Pedro M Alzari, Marcelo E Guerin (2014)

Rv2466c Mediates the Activation of TP053 To Kill Replicating and Non-replicating Mycobacterium tuberculosis

ACS chemical biology

David Albesa-Jové, Laurent R Chiarelli, Vadim Makarov, Maria Rosalia Pasca, Saioa Urresti, Giorgia Mori, Elena Salina, Anthony Vocat, Natalia Comino, Elisabeth Mohorko, Svetlana Ryabova, Bernhard Pfieiffer, Ana Luisa de Jesus Lopes Ribeiro, Ane Rodrigo-U (2014)

Structural basis of chitin oligosaccharide deacetylation

Angewandte Chemie International Edition

Eduardo Andrés*, David Albesa-Jové*, Xevi Biarnés, Bruno M Moerschbacher, Marcelo E Guerin, Antoni Planas (*equal contribution) (2014)

2013

Conformational Plasticity of the Essential Membrane-associated Mannosyltransferase PimA from Mycobacteria

Journal of Biological Chemistry

David Giganti, Jorge Alegre-Cebollada, Saioa Urresti, David Albesa-Jové, Ane Rodrigo-Unzueta, Natalia Comino, Michael Kachala, Sonia López-Fernández, Dmitri I Svergun, Julio M Fernández, Marcelo E Guerin (2013)

2012

Structural Versatility of Pyrene-2-(4, 4, 5, 5-tetramethyl-[1, 3, 2] dioxaborolane) and Pyrene-2, 7-bis (4, 4, 5, 5-tetramethyl-[1, 3, 2] dioxaborolane)

Crystal Growth & Design

Andrei S Batsanov, Judith AK Howard, David Albesa-Jové, Jonathan C Collings, Zhiqiang Liu, Ibraheem AI Mkhalid, Marie-He?le?ne Thibault, Todd B Marder (2012)

Mechanistic insights into the retaining glucosyl-3-phosphoglycerate synthase from mycobacteria

Journal of Biological Chemistry

Saioa Urresti*, David Albesa-Jové*, Francis Schaeffer, Ha T Pham, Devinder Kaur, Petra Gest, Mark J van der Woerd, Ana Carreras-González, Sonia López-Fernández, Pedro M Alzari, Patrick J Brennan, Mary Jackson, Marcelo E Guerin (*equal contribution) (2012)

2011

The electronic structures of diruthenium complexes containing an oligo (phenylene ethynylene) bridging ligand, and some related molecular structures Authors

Dalton Trans.

Wan M Khairul, Mark A Fox, Phil A Schauer, Dmitry S Yufit, David Albesa-Jové, Judith AK Howard, Paul J Low (2011)

Type VI Secretion System in Pseudomonas aeruginosa

Journal of Biological Chemistry

Abderrahman Hachani, Nadine S Lossi, Alexander Hamilton, Cerith Jones, Sophie Bleves, David Albesa-Jové, Alain Filloux (2011)

2010

Four distinct structural domains in Clostridium difficile toxin B visualized using SAXS

Journal of molecular biology

David Albesa-Jové, Thomas Bertrand, Elisabeth P Carpenter, Gemma V Swain, Jenson Lim, Jiancheng Zhang, Lesley F Haire, Nishi Vasisht, Veit Braun, Anton Lange, Christoph von Eichel-Streiber, Dmitri I Svergun, Neil F Fairweather, Katherine A Brown (2010)

2009

Structural insights into the molecular organization of the S-layer from Clostridium difficile

Molecular microbiology

Robert P Fagan, David Albesa-Jové, Omar Qazi, Dmitri I Svergun, Katherine A Brown, Neil F Fairweather (2009)

Syntheses, structures, two-photon absorption cross-sections and computed second hyperpolarisabilities of quadrupolar A–pi–A systems containing E-dimesitylborylethenyl acceptors

J. Mater. Chem.

Christopher D Entwistle, Jonathan C Collings, Andreas Steffen, Lars-Olof Pålsson, Andrew Beeby, David Albesa-Jové, Jacquelyn M Burke, Andrei S Batsanov, Judith AK Howard, Jackie A Mosely, Suk-Yue Poon, Wai-Yeung Wong, Fatima Ibersiene, Sofiane Fathallah, (2009)

2008

A Solid-State Dehydration Process Associated with a Significant Change in the Topology of Dihydrogen Phosphate Chains, Established from Powder X-ray Diffraction

Crystal Growth & Design

Albesa-Jové, David Pan, Zhigang Harris, Kenneth D. M. Uekusa, Hidehiro (2008)

Ruthenium complexes of C, C'-bis (ethynyl) carboranes: An investigation of electronic interactions mediated by spherical pseudo-aromatic spacers

Journal of the American Chemical Society

Mark A Fox, Rachel L Roberts, Thomas E Baines, Boris Le Guennic, Jean-François Halet, František Hartl, Dmitri S Yufit, David Albesa-Jové, Judith AK Howard, J Paul (2008)

2006

Ir-Catalyzed Borylation of C-H Bonds in N-Containing Heterocycles: Regioselectivity in the Synthesis of Heteroaryl Boronate Esters

Angewandte Chemie International Edition

Ibraheem AI Mkhalid, David N Coventry, David Albesa-Jove, Andrei S Batsanov, Judith AK Howard, Robin N Perutz, Todd B Marder (2006)

Synthesis, Crystal Structures, Linear and Nonlinear Optical Properties, and Theoretical Studies of (p-R-Phenyl)-,(p-R-Phenylethynyl)-, and (E)-[2-(p-R-Phenyl) ethenyl] dimesitylboranes and Related Compounds

Chemistry-A European Journal

Zheng Yuan, Christopher D Entwistle, Jonathan C Collings, David Albesa-Jové, Andrei S Batsanov, Judith AK Howard, Nicholas J Taylor, Hanns Martin Kaiser, Dieter E Kaufmann, Suk-Yue Poon, Wai-Yeung Wong, Christophe Jardin, Sofiane Fathallah, Abdou Boucekki (2006)

2005

Synthesis, optical properties, crystal structures and phase behaviour of symmetric, conjugated ethynylarene-based rigid rods with terminal carboxylate groups

Journal of Materials Chemistry

Fasina, Tolulope M Collings, Jonathan C Burke, Jacqueline M Batsanov, Andrei S Ward, Richard M Albesa-Jové, David Porrès, Laurent Beeby, Andrew Howard, Judith A.K. Scott, Andrew J Clegg, William Watt, Stephen W. Viney, Christopher Marder, Todd B. (2005)