David Albesa-Jové

Ikerbasque Research Associate, Biofisika Institute

Conoce a David

Ikerbasque Research Associate at Biofisika Institute.

Research line:

Structural Microbiology.

Previous research experience at CIC bioGUNE (ES), the Imperial College London and Durham University (UK).

PhD in Chemistry from the University of Birmingham (UK).

Publicaciones

2019

Quick-soaking of crystals reveals unprecedented insights into the catalytic mechanism of glycosyltransferases.

Methods in Enzymology

David Albesa-Jové, Javier O. Cifuente, Beatriz Trastoy, Marcelo E. Guerin (2019)

Regulation of Human Hsc70 ATPase and Chaperone Activities by Apg2: Role of the Acidic Subdomain

J Mol Biol

Cabrera Y, Dublang L, Fernández-Higuero JA, Albesa-Jové D, Lucas M, Viguera AR, Guerin ME, Vilar JMG, Muga A, Moro F (2019)

2018

The Molecular Mechanism of Substrate Recognition and Catalysis of the Membrane Acyltransferase PatA from Mycobacteria

ACS Chemical Biology

Montse Tersa, Lluís Raich, David Albesa-Jové, Beatriz Trastoy, Jacques Prandi, Martine Gilleron, Carme Rovira, Marcelo E Guerin (2018)

2017

Structural Snapshots and Loop Dynamics along the Catalytic Cycle of Glycosyltransferase GpgS

Structure

David Albesa-Jové, Javier Romero-García, Enea Sancho-Vaello, F-Xabier Contreras, Ane Rodrigo-Unzueta, Natalia Comino, Ana Carreras-González, Pedro Arrasate, Saioa Urresti, Xevi Biarnés, Antoni Planas, Marcelo E Guerin (2017)

The antibacterial prodrug activator Rv2466c is a mycothiol-dependent reductase in the oxidative stress response of Mycobacterium tuberculosis

Journal of Biological Chemistry

Leonardo Astolfi Rosado, Khadija Wahni, Giulia Degiacomi, Brandan Pedre, David Young, G Alfonso, Francesca Boldrin, Edo Martens, Laura Marcos-Pascual, Enea Sancho-Vaello, David Albesa-Jové, Roberta Provvedi, Charlotte Martin, Vadim Makarov, Wim Versées, G (2017)

Structural Snapshots of alpha-1, 3-Galactosyltransferase with Native Substrates: Insight into the Catalytic Mechanism of Retaining Glycosyltransferases

Angewandte Chemie

David Albesa-Jové*, M Ángela Sainz-Polo, Alberto Marina, Marcelo E Guerin* (corresponding author) (2017)

Structural basis of phosphatidylinositol mannosides biosynthesis in mycobacteria

Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids

Enea Sancho-Vaello, David Albesa-Jové, Ane Rodrigo-Unzueta, Marcelo E Guerin (2017)

2016

Structural basis for selective recognition of acyl chains by the membrane-associated acyltransferase PatA

Nature Communications

David Albesa-Jové, Zuzana Svetlíková, Montse Tersa, Enea Sancho-Vaello, Ana Carreras-González, Pascal Bonnet, Pedro Arrasate, Ander Eguskiza, Shiva K Angala, Javier O Cifuente, Jana Korduláková, Mary Jackson, Katarína Mikušová, Marcelo E Guerin (2016)

TssA forms a gp6-like ring attached to the type VI secretion sheath

The EMBO Journal

Sara Planamente, Osman Salih, Eleni Manoli, David Albesa?Jové, Paul S Freemont, Alain Filloux (2016)

Structural Basis of Glycogen Biosynthesis Regulation in Bacteria

Structure

Javier O Cifuente, Natalia Comino, Julene Madariaga-Marcos, Sonia López-Fernández, Mikel García-Alija, Jon Agirre, David Albesa-Jové*, Marcelo E Guerin* (Corresponding authors) (2016)

The conformational plasticity of glycosyltransferases

Current Opinion in Structural Biology

David Albesa-Jové, Marcelo E Guerin (2016)

2015

Secondary structure reshuffling modulates glycosyltransferase function at the membrane

Nature chemical biology

David Giganti, David Albesa-Jové, Saioa Urresti, Ane Rodrigo-Unzueta, Mariano A Martínez, Natalia Comino, Nathalie Barilone, Marco Bellinzoni, Alexandre Chenal, Marcelo E Guerin, Pedro M Alzari (2015)

A Native Ternary Complex Trapped in a Crystal Reveals the Catalytic Mechanism of a Retaining Glycosyltransferase

Angewandte Chemie

David Albesa-Jové, Fernanda Mendoza, Ane Rodrigo-Unzueta, Fernando Gomollón-Bel, Javier O Cifuente, Saioa Urresti, Natalia Comino, Hansel Gómez, Javier Romero-García, José M Lluch, Enea Sancho-Vaello, Xevi Biarnés, Antoni Planas, Pedro Merino, Laura Masgr (2015)

The redox state regulates the conformation of Rv2466c to activate the antitubercular prodrug TP053

Journal of Biological Chemistry

David Albesa-Jové, Natalia Comino, Montse Tersa, Elisabeth Mohorko, Saioa Urresti, Elisa Dainese, Laurent R Chiarelli, Maria Rosalia Pasca, Riccardo Manganelli, Vadim Makarov, Giovanna Riccardi, Dmitri I Svergun, Rudi Glockshuber, Marcelo E Guerin (2015)

2014

Iridium-catalyzed C–H borylation of pyridines

Organic & Biomolecular Chemistry

Sadler, Scott A. Tajuddin, Hazmi Mkhalid, Ibraheem A. I. Batsanov, Andrei S. Albesa-Jové, David Cheung, Man Sing Maxwell, Aoife C. Shukla, Lena Roberts, Bryan Blakemore, David C. Lin, Zhenyang Marder, Todd B. Steel, Patrick G. (2014)

Structure–function relationships of membrane-associated GT-B glycosyltransferases

Glycobiology

David Albesa-Jové, David Giganti, Mary Jackson, Pedro M Alzari, Marcelo E Guerin (2014)

Rv2466c Mediates the Activation of TP053 To Kill Replicating and Non-replicating Mycobacterium tuberculosis

ACS chemical biology

David Albesa-Jové, Laurent R Chiarelli, Vadim Makarov, Maria Rosalia Pasca, Saioa Urresti, Giorgia Mori, Elena Salina, Anthony Vocat, Natalia Comino, Elisabeth Mohorko, Svetlana Ryabova, Bernhard Pfieiffer, Ana Luisa de Jesus Lopes Ribeiro, Ane Rodrigo-U (2014)

Structural basis of chitin oligosaccharide deacetylation

Angewandte Chemie International Edition

Eduardo Andrés*, David Albesa-Jové*, Xevi Biarnés, Bruno M Moerschbacher, Marcelo E Guerin, Antoni Planas (*equal contribution) (2014)

2013

Conformational Plasticity of the Essential Membrane-associated Mannosyltransferase PimA from Mycobacteria

Journal of Biological Chemistry

David Giganti, Jorge Alegre-Cebollada, Saioa Urresti, David Albesa-Jové, Ane Rodrigo-Unzueta, Natalia Comino, Michael Kachala, Sonia López-Fernández, Dmitri I Svergun, Julio M Fernández, Marcelo E Guerin (2013)

2012

Structural Versatility of Pyrene-2-(4, 4, 5, 5-tetramethyl-[1, 3, 2] dioxaborolane) and Pyrene-2, 7-bis (4, 4, 5, 5-tetramethyl-[1, 3, 2] dioxaborolane)

Crystal Growth & Design

Andrei S Batsanov, Judith AK Howard, David Albesa-Jové, Jonathan C Collings, Zhiqiang Liu, Ibraheem AI Mkhalid, Marie-He?le?ne Thibault, Todd B Marder (2012)

Mechanistic insights into the retaining glucosyl-3-phosphoglycerate synthase from mycobacteria

Journal of Biological Chemistry

Saioa Urresti*, David Albesa-Jové*, Francis Schaeffer, Ha T Pham, Devinder Kaur, Petra Gest, Mark J van der Woerd, Ana Carreras-González, Sonia López-Fernández, Pedro M Alzari, Patrick J Brennan, Mary Jackson, Marcelo E Guerin (*equal contribution) (2012)

2011

The electronic structures of diruthenium complexes containing an oligo (phenylene ethynylene) bridging ligand, and some related molecular structures Authors

Dalton Trans.

Wan M Khairul, Mark A Fox, Phil A Schauer, Dmitry S Yufit, David Albesa-Jové, Judith AK Howard, Paul J Low (2011)

Type VI Secretion System in Pseudomonas aeruginosa

Journal of Biological Chemistry

Abderrahman Hachani, Nadine S Lossi, Alexander Hamilton, Cerith Jones, Sophie Bleves, David Albesa-Jové, Alain Filloux (2011)

2010

Four distinct structural domains in Clostridium difficile toxin B visualized using SAXS

Journal of molecular biology

David Albesa-Jové, Thomas Bertrand, Elisabeth P Carpenter, Gemma V Swain, Jenson Lim, Jiancheng Zhang, Lesley F Haire, Nishi Vasisht, Veit Braun, Anton Lange, Christoph von Eichel-Streiber, Dmitri I Svergun, Neil F Fairweather, Katherine A Brown (2010)

2009

Structural insights into the molecular organization of the S-layer from Clostridium difficile

Molecular microbiology

Robert P Fagan, David Albesa-Jové, Omar Qazi, Dmitri I Svergun, Katherine A Brown, Neil F Fairweather (2009)

Syntheses, structures, two-photon absorption cross-sections and computed second hyperpolarisabilities of quadrupolar A–pi–A systems containing E-dimesitylborylethenyl acceptors

J. Mater. Chem.

Christopher D Entwistle, Jonathan C Collings, Andreas Steffen, Lars-Olof Pålsson, Andrew Beeby, David Albesa-Jové, Jacquelyn M Burke, Andrei S Batsanov, Judith AK Howard, Jackie A Mosely, Suk-Yue Poon, Wai-Yeung Wong, Fatima Ibersiene, Sofiane Fathallah, (2009)

2008

A Solid-State Dehydration Process Associated with a Significant Change in the Topology of Dihydrogen Phosphate Chains, Established from Powder X-ray Diffraction

Crystal Growth & Design

Albesa-Jové, David Pan, Zhigang Harris, Kenneth D. M. Uekusa, Hidehiro (2008)

Ruthenium complexes of C, C'-bis (ethynyl) carboranes: An investigation of electronic interactions mediated by spherical pseudo-aromatic spacers

Journal of the American Chemical Society

Mark A Fox, Rachel L Roberts, Thomas E Baines, Boris Le Guennic, Jean-François Halet, František Hartl, Dmitri S Yufit, David Albesa-Jové, Judith AK Howard, J Paul (2008)

2006

Ir-Catalyzed Borylation of C-H Bonds in N-Containing Heterocycles: Regioselectivity in the Synthesis of Heteroaryl Boronate Esters

Angewandte Chemie International Edition

Ibraheem AI Mkhalid, David N Coventry, David Albesa-Jove, Andrei S Batsanov, Judith AK Howard, Robin N Perutz, Todd B Marder (2006)

Synthesis, Crystal Structures, Linear and Nonlinear Optical Properties, and Theoretical Studies of (p-R-Phenyl)-,(p-R-Phenylethynyl)-, and (E)-[2-(p-R-Phenyl) ethenyl] dimesitylboranes and Related Compounds

Chemistry-A European Journal

Zheng Yuan, Christopher D Entwistle, Jonathan C Collings, David Albesa-Jové, Andrei S Batsanov, Judith AK Howard, Nicholas J Taylor, Hanns Martin Kaiser, Dieter E Kaufmann, Suk-Yue Poon, Wai-Yeung Wong, Christophe Jardin, Sofiane Fathallah, Abdou Boucekki (2006)

2005

Synthesis, optical properties, crystal structures and phase behaviour of symmetric, conjugated ethynylarene-based rigid rods with terminal carboxylate groups

Journal of Materials Chemistry

Fasina, Tolulope M Collings, Jonathan C Burke, Jacqueline M Batsanov, Andrei S Ward, Richard M Albesa-Jové, David Porrès, Laurent Beeby, Andrew Howard, Judith A.K. Scott, Andrew J Clegg, William Watt, Stephen W. Viney, Christopher Marder, Todd B. (2005)