Ana Gimeno

Ikerbasque Research Fellow, CIC bioGUNE

Currently works at CIC bioGUNE in the Chemical Glycobiology Lab

Research line:

Chemical Glycobiology

Graduation Award, FPI Predoctoral Fellow, Juan de la Cierva Postdoctoral Fellow, Ramón y Cajal Fellow

Previous research experience at Utrecht University (The Netherlands), University of Oviedo (Spain), Max-Plank Research Institute (Germany), University of Santiago de Compostela (Spain), University of Valencia (Spain)

Doctor in Chemistry (2014) from University of Valencia, Spain

Publications

2026

Article / Rational design of heparin antagonist: Guanidine-based mimetics unveil key carbohydrate-carbohydrate interactions

Ankita Chandra, Ana Gimeno, María Payá-García, Preeti Ravindra Bhoge, Virendrasinh Mahida, Jesús Jiménez-Barbero, Raghavendra Kikkeri

Article / Polyamine-dependent metabolic shielding regulates alternative splicing

Nature

Amaia Zabala-Letona, Mikel Pujana-Vaquerizo, Belen Martinez-Laosa, Maria Ponce-Rodriguez, Saioa Garcia-Longarte, Isabel Mendizabal, Ana Gimeno, Malgorzata Rogalska, Joycelyn Tan, Diana Cabrera, Sebastiaan van Liempd, Pilar Ximenez-Embun, Sergio Espinosa, Maider Fagoaga-Eugui, Francesca Peccati, Maciej Zakrzewski, Ianire Astobiza, Mikel Arana-Castañares, Sarah Cherkaoui, Maria Sendino, Inés Martín-Barros, Amaia Ercilla, Laura Bozal-Basterra, Onintza Carlevaris, Amaia Arruabarrena-Aristorena, Encarnación Pérez-Andrés, Telmo Santamaría-Zamorano, Juan A. Ferrer-Bonsoms, Fernando Carazo, Maciej Cieśla, Cesar Lobato, Joan Seoane, Natalia Martín-Martín, Rosa Barrio, James D. Sutherland, Ana M. Aransay, Juan Manuel Falcón-Pérez, Barbara Martínez-Pastor, Angel Rubio, Francisco J. Blanco, Michael D. Hogarty, Raphael J. Morscher, Edurne Berra, Remigiusz A. Serwa, Jesús Jiménez-Barbero, Gonzalo Jiménez-Osés, Alejo Efeyan, Lydia Finley, Jose M. Lizcano, Javier Muñoz, Juan Valcarcel & Arkaitz Carracedo

2025

Article / Presentation Is Essential for Glycan-Lectin Recognition at the Molecular and Cellular Levels: The Interaction of Tumor-Associated O-Glycans with the Macrophage Galactose-Type Lectin

Presentation Is Essential for Glycan-Lectin Recognition at the Molecular and Cellular Levels: The Interaction of Tumor-Associated O-Glycans with the Macrophage Galactose-Type Lectin

Ana Sofia GrossoAna DinizCátia O. SoaresFelix GoerdelerAna GimenoPedro CoelhoHelena CoelhoCarlos D. L. LimaBenedita PinheiroMarta G. LeteFayna Garcia-MartinThapakorn JaroentomeechaiJoana GomesCelso A. ReisUlrika WesterlindFrancisco CorzanaAngelina S. PalmaHenrik ClausenJesús Jiménez-BarberoSandra J. van VlietYoshiki NarimatsuFilipa Marcelo*

Article / Decoding the Molecular Basis of the Specificity of an Anti-sTn Antibody

Jacs Au

Soares, C.O.; Laugieri, M.E.; Grosso, A.S.; Natale, M.; Coelho, H.; Behren, S.; Yu, J.; Cai, H.; Franconetti, A.; Oyenarte, I.; Magnasco, M.; Gimeno, A.; Ramos, N.; Chai, W.; Corzana, F.; Westerlind, U.; Jiménez-Barbero, J.; Palma, A.S.; Videira, P.A.; Ereño-Orbea, J.; Marcelo, F.

Article / Unravelling structure-function interactions between fluorinated heparan sulfate mimetics and signaling proteins

Rsc Chemical Biology

Mahida, V.; Raigawali, R.; González, P.; Gimeno, A.; Leviatan Ben-Arye, S.; Anand, S.; Mardhekar, S.; Jiménez-Barbero, J.; Padler-Karavani, V.; Kikkeri, R.

2024

Article / Site-Specific Glyco-Tagging of Native Proteins for the Development of Biologicals

Journal of American Chemical Society

A. Gimeno, A. M. Ehlers, S. Delgado, J-W. H. Langenbach, L. J. van den Bos, J. A.W. Kruijtzer, B. G.A. Guigas, G-J. Boons.

Article / Disentangling Glycan-Protein Interactions: Nuclear Magnetic Resonance (NMR) to the Rescue

Journal of Visualized Experiments

Bertuzzi, S.; Poveda, A.; Ardá, A.; Gimeno, A.; Jiménez-Barbero, J.

Article / Solid-Phase-Supported Chemoenzymatic Synthesis and Analysis of Chondroitin Sulfate Proteoglycan Glycopeptides

Angewandte Chemie International Edition

Lin, P.h.; Xu, Y.; Bali, S.K.; Kim, J.; Gimeno, A.; Roberts, E.T.; James, D.; Almeida, N.M.S.; Loganathan, N.; Fan, F.; Wilson, A.K.; Jonathan Amster, I.; Moremen, K.W.; Liu, J.; Jiménez-Barbero, J.; Huang, X.

Article / Exploring galectin interactions with human milk oligosaccharides and blood group antigens identifies BGA6 as a functional galectin-4 ligand

Journal of Biological Chemistry

Cagnoni, A.J.; Massaro, M.; Cutine, A.M.; Gimeno, A.; Pérez-Sáez, J.M.; Manselle Cocco, M.N.; Maller, S.M.; Di Lella, S.; Jiménez-Barbero, J.; Ardá, A.; Rabinovich, G.A.; Mariño, K.V.

Article / Unprecedented selectivity for homologous lectin targets: differential targeting of the viral receptors L-SIGN and DC-SIGN

Chemical Science

Delaunay, C.; Pollastri, S.; Thepaut, M.; Cavazzoli, G.; Belvisi, L.; Bouchikri, C.; Labiod, N.; Lasala, F.; Gimeno, A.; Franconetti, A.; Jimenez-Barbero, J.; Arda, A.; Delgado, R.; Bernardi, A.; Fieschi, F.

Article / Unveiling the GT114 family: Structural characterization of A075L, a glycosyltransferase from Paramecium bursaria chlorella virus-1 (PBCV-1)

Protein Science

Laugieri, M.E.; Speciale, I.; Gimeno, A.; Lin, S.; Byers, B.W.; Poveda, A.; Núñez-Franco, R.; Iturrioz, I.; Moure, M.J.; Jiménez-Osés, G.; Russo-Krauss, I.; Notaro, A.; Van Etten, J.L.; Lowary, T.L.; Jimenez-Barbero, J.; De Castro, C.; Tonetti, M.; Rojas, A.L.

Review / NMR investigations of glycan conformation, dynamics, and interactions

Progress in Nuclear Magnetic Resonance Spectroscopy

Angulo, J.; Ardá, A.; Bertuzzi, S.; Canales, A.; Ereño-Orbea, J.; Gimeno, A.; Gomez-Redondo, M.; Muñoz-García, J.C.; Oquist, P.; Monaco, S.; Poveda, A.; Unione, L.; Jiménez-Barbero, J.

2023

Article / Synthetic Zwitterionic Streptococcus pneumoniae Type 1 Oligosaccharides Carrying Labile O-Acetyl Esters

Angewandte Chemie International Edition

Wang, Z.; Gimeno, A.; Lete, M.G.; Overkleeft, H.S.; van der Marel, G.A.; Chiodo, F.; Jiménez-Barbero, J.; Codée, J.D.C.